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Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor

Thyroid eye disease (TED) can lead to scar formation and tissue remodeling in the orbital space. In severe cases, the scarring process leads to sight-threatening pathophysiology. There is no known effective way to prevent scar formation in TED patients, or to reverse scarring once it occurs. In this...

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Detalles Bibliográficos
Autores principales: Hammond, Christine L., Roztocil, Elisa, Phipps, Richard P., Feldon, Steven E., Woeller, Collynn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752849/
https://www.ncbi.nlm.nih.gov/pubmed/31536596
http://dx.doi.org/10.1371/journal.pone.0222779