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Integrating thermodynamic and sequence contexts improves protein-RNA binding prediction

Predicting RNA-binding protein (RBP) specificity is important for understanding gene expression regulation and RNA-mediated enzymatic processes. It is widely believed that RBP binding specificity is determined by both the sequence and structural contexts of RNAs. Existing approaches, including tradi...

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Detalles Bibliográficos
Autores principales: Su, Yufeng, Luo, Yunan, Zhao, Xiaoming, Liu, Yang, Peng, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752863/
https://www.ncbi.nlm.nih.gov/pubmed/31483777
http://dx.doi.org/10.1371/journal.pcbi.1007283