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Integrating thermodynamic and sequence contexts improves protein-RNA binding prediction
Predicting RNA-binding protein (RBP) specificity is important for understanding gene expression regulation and RNA-mediated enzymatic processes. It is widely believed that RBP binding specificity is determined by both the sequence and structural contexts of RNAs. Existing approaches, including tradi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752863/ https://www.ncbi.nlm.nih.gov/pubmed/31483777 http://dx.doi.org/10.1371/journal.pcbi.1007283 |