Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation

Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor important in diverse biological processes including cell proliferation and survival. Upregulation of EGFR activity due to over-expression or mutation is widely implicated in cancer. Activating somatic mutations of the EGFR kinase...

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Detalles Bibliográficos
Autores principales: Tamirat, Mahlet Z., Koivu, Marika, Elenius, Klaus, Johnson, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752865/
https://www.ncbi.nlm.nih.gov/pubmed/31536605
http://dx.doi.org/10.1371/journal.pone.0222814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752865/
https://www.ncbi.nlm.nih.gov/pubmed/31536605
http://dx.doi.org/10.1371/journal.pone.0222814

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