Cargando…

RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses

All synapses require fusion-competent vesicles and coordinated Ca(2+)-secretion coupling for neurotransmission, yet functional and anatomical properties are diverse across different synapse types. We show that the presynaptic protein RIM-BP2 has diversified functions in neurotransmitter release at d...

Descripción completa

Detalles Bibliográficos
Autores principales: Brockmann, Marisa M, Maglione, Marta, Willmes, Claudia G, Stumpf, Alexander, Bouazza, Boris A, Velasquez, Laura M, Grauel, M Katharina, Beed, Prateep, Lehmann, Martin, Gimber, Niclas, Schmoranzer, Jan, Sigrist, Stephan J, Rosenmund, Christian, Schmitz, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752948/
https://www.ncbi.nlm.nih.gov/pubmed/31535974
http://dx.doi.org/10.7554/eLife.43243