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Evolution of Yin and Yang isoforms of a chromatin remodeling subunit precedes the creation of two genes

Genes can encode multiple isoforms, broadening their functions and providing a molecular substrate to evolve phenotypic diversity. Evolution of isoform function is a potential route to adapt to new environments. Here we show that de novo, beneficial alleles in the nurf-1 gene became fixed in two lab...

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Detalles Bibliográficos
Autores principales: Xu, Wen, Long, Lijiang, Zhao, Yuehui, Stevens, Lewis, Felipe, Irene, Munoz, Javier, Ellis, Ronald E, McGrath, Patrick T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752949/
https://www.ncbi.nlm.nih.gov/pubmed/31498079
http://dx.doi.org/10.7554/eLife.48119