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Beta-defensins and analogs in Helicobacter pylori infections: mRNA expression levels, DNA methylation, and antibacterial activity

Antimicrobial peptides can protect the gastric mucosa from bacteria, but Helicobacter pylori (H. pylori) can equally colonize the gastric apparatus. To understand beta-defensin function in H. pylori-associated chronic gastritis, we investigated susceptibility, human beta-defensin mRNA expression, an...

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Detalles Bibliográficos
Autores principales: Pero, Raffaela, Angrisano, Tiziana, Brancaccio, Mariarita, Falanga, Annarita, Lombardi, Lucia, Natale, Francesco, Laneri, Sonia, Lombardo, Barbara, Galdiero, Stefania, Scudiero, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752957/
https://www.ncbi.nlm.nih.gov/pubmed/31537016
http://dx.doi.org/10.1371/journal.pone.0222295