LOSS OF THE TUMOR SUPPRESSOR, TP53, ENHANCES THE ANDROGEN RECEPTOR MEDIATED ONCOGENIC TRANSFORMATION AND TUMOR DEVELOPMENT IN THE MOUSE PROSTATE

Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations in prostate tumorigenesis is largely unknown....

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Detalles Bibliográficos
Autores principales: He, Yongfeng, Johnson, Daniel T., Yang, Julie S., Wu, Huiqing, You, Sungyong, Yoon, Junhee, Lee, Dong-Hong, Kim, Won Kyung, Aldahl, Joseph, Le, Vien, Hooker, Erika, Yu, Eun-Jeong, Geardts, Joseph, Cardiff, Robert D., Sun, Zijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752978/
https://www.ncbi.nlm.nih.gov/pubmed/31358900
http://dx.doi.org/10.1038/s41388-019-0901-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752978/
https://www.ncbi.nlm.nih.gov/pubmed/31358900
http://dx.doi.org/10.1038/s41388-019-0901-8

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