NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress

Transport of dietary cholesterol from endocytic organelles to the endoplasmic reticulum (ER) is essential for cholesterol homoeostasis, but the mechanism and regulation of this transport remains poorly defined. Membrane contact sites (MCS), microdomains of close membrane apposition, are gaining atte...

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Detalles Bibliográficos
Autores principales: Höglinger, D., Burgoyne, T., Sanchez-Heras, E., Hartwig, P., Colaco, A., Newton, J., Futter, C. E., Spiegel, S., Platt, F. M., Eden, E. R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753064/
https://www.ncbi.nlm.nih.gov/pubmed/31537798
http://dx.doi.org/10.1038/s41467-019-12152-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753064/
https://www.ncbi.nlm.nih.gov/pubmed/31537798
http://dx.doi.org/10.1038/s41467-019-12152-2

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