Cargando…
Process development for scale-up production of a therapeutic L-asparaginase by Streptomyces brollosae NEAE-115 from shake flasks to bioreactor
L-asparaginase is a promising enzyme that has a wide range of significant applications including cancer therapy and starchy food industries. The statistical design of Plackett–Burman and face centered central composite design were employed to optimize L-asparaginase production by Streptomyces brollo...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753079/ https://www.ncbi.nlm.nih.gov/pubmed/31537817 http://dx.doi.org/10.1038/s41598-019-49709-6 |