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Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer

Prostate cancer is a highly heterogeneous disease and typically multiple distinct cancer foci are present at primary diagnosis. Molecular classification of prostate cancer can potentially aid the precision of diagnosis and treatment. A promising genomic classifier was published by The Cancer Genome...

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Detalles Bibliográficos
Autores principales: Carm, Kristina Totland, Hoff, Andreas M., Bakken, Anne Cathrine, Axcrona, Ulrika, Axcrona, Karol, Lothe, Ragnhild A., Skotheim, Rolf I., Løvf, Marthe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753093/
https://www.ncbi.nlm.nih.gov/pubmed/31537872
http://dx.doi.org/10.1038/s41598-019-49964-7