Atroposelective antibodies as a designed protein scaffold for artificial metalloenzymes

Design and engineering of protein scaffolds are crucial to create artificial metalloenzymes. Herein we report the first example of C-C bond formation catalyzed by artificial metalloenzymes, which consist of monoclonal antibodies (mAbs) and C(2) symmetric metal catalysts. Prepared as a tailored prote...

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Detalles Bibliográficos
Autores principales: Adachi, Takuma, Harada, Akira, Yamaguchi, Hiroyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753118/
https://www.ncbi.nlm.nih.gov/pubmed/31537832
http://dx.doi.org/10.1038/s41598-019-49844-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753118/
https://www.ncbi.nlm.nih.gov/pubmed/31537832
http://dx.doi.org/10.1038/s41598-019-49844-0

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