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Atroposelective antibodies as a designed protein scaffold for artificial metalloenzymes
Design and engineering of protein scaffolds are crucial to create artificial metalloenzymes. Herein we report the first example of C-C bond formation catalyzed by artificial metalloenzymes, which consist of monoclonal antibodies (mAbs) and C(2) symmetric metal catalysts. Prepared as a tailored prote...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753118/ https://www.ncbi.nlm.nih.gov/pubmed/31537832 http://dx.doi.org/10.1038/s41598-019-49844-0 |