Discovering genetic interactions bridging pathways in genome-wide association studies

Genetic interactions have been reported to underlie phenotypes in a variety of systems, but the extent to which they contribute to complex disease in humans remains unclear. In principle, genome-wide association studies (GWAS) provide a platform for detecting genetic interactions, but existing metho...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Gang, Wang, Wen, Paunic, Vanja, Heydari, Hamed, Costanzo, Michael, Liu, Xiaoye, Liu, Xiaotong, VanderSluis, Benjamin, Oately, Benjamin, Steinbach, Michael, Van Ness, Brian, Schadt, Eric E., Pankratz, Nathan D., Boone, Charles, Kumar, Vipin, Myers, Chad L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753138/
https://www.ncbi.nlm.nih.gov/pubmed/31537791
http://dx.doi.org/10.1038/s41467-019-12131-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753138/
https://www.ncbi.nlm.nih.gov/pubmed/31537791
http://dx.doi.org/10.1038/s41467-019-12131-7

Ejemplares similares