Transcription-dependent targeting of Hda1C to hyperactive genes mediates H4-specific deacetylation in yeast

In yeast, Hda1 histone deacetylase complex (Hda1C) preferentially deacetylates histones H3 and H2B, and functionally interacts with Tup1 to repress transcription. However, previous studies identified global increases in histone H4 acetylation in cells lacking Hda1, a component of Hda1C. Here, we fin...

Descripción completa

Detalles Bibliográficos
Autores principales: Ha, So Dam, Ham, Seokjin, Kim, Min Young, Kim, Ji Hyun, Jang, Insoon, Lee, Bo Bae, Lee, Min Kyung, Hwang, Jin-Taek, Roh, Tae-Young, Kim, TaeSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753149/
https://www.ncbi.nlm.nih.gov/pubmed/31537788
http://dx.doi.org/10.1038/s41467-019-12077-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753149/
https://www.ncbi.nlm.nih.gov/pubmed/31537788
http://dx.doi.org/10.1038/s41467-019-12077-w

Ejemplares similares