Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade

MicroRNAs (miRs) downregulate or upregulate the mRNA level by binding to the 3′-untranslated region (3′UTR) of target gene. Dysregulated miR levels can be used as biomarkers of Parkinson’s disease (PD) and could participate in the etiology of PD. In the present study, 45 brain-enriched miRs were eva...

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Detalles Bibliográficos
Autores principales: Chiu, Ching-Chi, Yeh, Tu-Hsueh, Chen, Rou-Shayn, Chen, Hua-Chien, Huang, Ying-Zu, Weng, Yi-Hsin, Cheng, Yi-Chuan, Liu, Yu-Chuan, Cheng, Ann-Joy, Lu, Ya-Ching, Chen, Yu-Jie, Lin, Yan-Wei, Hsu, Chia-Chen, Chen, Ying-Ling, Lu, Chin-Song, Wang, Hung-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753175/
https://www.ncbi.nlm.nih.gov/pubmed/31572127
http://dx.doi.org/10.3389/fncel.2019.00399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753175/
https://www.ncbi.nlm.nih.gov/pubmed/31572127
http://dx.doi.org/10.3389/fncel.2019.00399

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