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Inhibition of IL-1β by Aliskiren Improved Renal AQP2 Expression and Urinary Concentration Defect in Ureteral Obstruction and Release

We previously demonstrated that ureteral obstruction is associated with a urinary concentrating defect and reduced expression of renal aquaporins (AQPs), in which the renin–angiotensin system (RAS) may play an important role. The aims of the present study were to examine whether the renin inhibitor...

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Detalles Bibliográficos
Autores principales: Hu, Shan, Xie, Haixia, Luo, Renfei, Feng, Pinning, Liu, Qiaojuan, Han, Mengke, Kong, Yonglun, Zou, Xuenong, Wang, Weidong, Li, Chunling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753185/
https://www.ncbi.nlm.nih.gov/pubmed/31572210
http://dx.doi.org/10.3389/fphys.2019.01157