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(18)F-Labeled Cyclized α-Melanocyte-Stimulating Hormone Derivatives for Imaging Human Melanoma Xenograft with Positron Emission Tomography

Since metastatic melanoma is deadly, early diagnosis thereof is crucial for managing the disease. We recently developed α-melanocyte-stimulating hormone (αMSH) derivatives, [(68)Ga]Ga-CCZ01048 and [(18)F]CCZ01064, that target the melanocortin 1 receptor (MC1R) for mouse melanoma imaging. In this stu...

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Detalles Bibliográficos
Autores principales: Zhang, Chengcheng, Zhang, Zhengxing, Merkens, Helen, Zeisler, Jutta, Colpo, Nadine, Hundal-Jabal, Navjit, Perrin, David M., Lin, Kuo-Shyan, Bénard, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753210/
https://www.ncbi.nlm.nih.gov/pubmed/31537869
http://dx.doi.org/10.1038/s41598-019-50014-5