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Xanthoceraside Could Ameliorate Alzheimer’s Disease Symptoms of Rats by Affecting the Gut Microbiota Composition and Modulating the Endogenous Metabolite Levels

Xanthoceraside (XAN) is a natural-derived compound with anti-Alzheimer activity from the husks of Xanthoceras sorbifolia. Although its therapeutic effect had been confirmed in previous studies, the mechanism was still unclear due to its poor solubility and low permeability. In this study, the pharma...

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Detalles Bibliográficos
Autores principales: Zhou, Hongxu, Tai, Jingjie, Xu, Haiyan, Lu, Xiumei, Meng, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753234/
https://www.ncbi.nlm.nih.gov/pubmed/31572201
http://dx.doi.org/10.3389/fphar.2019.01035