Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis

Repurposing existing drugs for cancer treatment is an effective strategy. An approved antipsychotic drug, trifluoperazine (TFP), has been reported to have potential anticancer effects against several cancer types. Here, we investigated the effect and molecular mechanism of TFP in colorectal cancer (...

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Detalles Bibliográficos
Autores principales: Xia, Yong, Jia, Chengsen, Xue, Qiang, Jiang, Jinrui, Xie, Yao, Wang, Ranran, Ran, Zhiqiang, Xu, Fuyan, Zhang, Yiwen, Ye, Tinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753363/
https://www.ncbi.nlm.nih.gov/pubmed/31572198
http://dx.doi.org/10.3389/fphar.2019.01029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753363/
https://www.ncbi.nlm.nih.gov/pubmed/31572198
http://dx.doi.org/10.3389/fphar.2019.01029

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