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Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis
Repurposing existing drugs for cancer treatment is an effective strategy. An approved antipsychotic drug, trifluoperazine (TFP), has been reported to have potential anticancer effects against several cancer types. Here, we investigated the effect and molecular mechanism of TFP in colorectal cancer (...
Autores principales: | Xia, Yong, Jia, Chengsen, Xue, Qiang, Jiang, Jinrui, Xie, Yao, Wang, Ranran, Ran, Zhiqiang, Xu, Fuyan, Zhang, Yiwen, Ye, Tinghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753363/ https://www.ncbi.nlm.nih.gov/pubmed/31572198 http://dx.doi.org/10.3389/fphar.2019.01029 |
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