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Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy
Random-pattern skin flap replantation is commonly used to repair skin defects during plastic and reconstructive surgery. However, flap necrosis due to ischemia and ischemia–reperfusion injury limits clinical applications. Betulinic acid, a plant-derived pentacyclic triterpene, may facilitate flap su...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753397/ https://www.ncbi.nlm.nih.gov/pubmed/31572190 http://dx.doi.org/10.3389/fphar.2019.01017 |