Functional interplay between Mediator and RNA polymerase II in Rad2/XPG loading to the chromatin

Transcription and maintenance of genome integrity are fundamental cellular functions. Deregulation of transcription and defects in DNA repair lead to serious pathologies. The Mediator complex links RNA polymerase (Pol) II transcription and nucleotide excision repair via Rad2/XPG endonuclease. Howeve...

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Detalles Bibliográficos
Autores principales: Georges, Adrien, Gopaul, Diyavarshini, Denby Wilkes, Cyril, Giordanengo Aiach, Nathalie, Novikova, Elizaveta, Barrault, Marie-Bénédicte, Alibert, Olivier, Soutourina, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753472/
https://www.ncbi.nlm.nih.gov/pubmed/31299084
http://dx.doi.org/10.1093/nar/gkz598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753472/
https://www.ncbi.nlm.nih.gov/pubmed/31299084
http://dx.doi.org/10.1093/nar/gkz598

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