Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent

A common mechanism for inducibly controlling protein function relies on reconstitution of split protein fragments using chemical or light-induced dimerization domains. A protein is split into fragments that are inactive on their own, but can be reconstituted after dimerization. As many split protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Meador, Kyle, Wysoczynski, Christina L, Norris, Aaron J, Aoto, Jason, Bruchas, Michael R, Tucker, Chandra L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753482/
https://www.ncbi.nlm.nih.gov/pubmed/31287871
http://dx.doi.org/10.1093/nar/gkz585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753482/
https://www.ncbi.nlm.nih.gov/pubmed/31287871
http://dx.doi.org/10.1093/nar/gkz585

Ejemplares similares