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Structural and phenotypic analysis of Chikungunya virus RNA replication elements

Chikungunya virus (CHIKV) is a re-emerging, pathogenic Alphavirus transmitted to humans by Aedes spp. mosquitoes. We have mapped the RNA structure of the 5′ region of the CHIKV genome using selective 2′-hydroxyl acylation analysed by primer extension (SHAPE) to investigate intramolecular base-pairin...

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Detalles Bibliográficos
Autores principales: Kendall, Catherine, Khalid, Henna, Müller, Marietta, Banda, Dominic H, Kohl, Alain, Merits, Andres, Stonehouse, Nicola J, Tuplin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753490/
https://www.ncbi.nlm.nih.gov/pubmed/31350895
http://dx.doi.org/10.1093/nar/gkz640