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KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity
CpG islands (CGIs) are associated with the majority of mammalian gene promoters and function to recruit chromatin modifying enzymes. It has therefore been proposed that CGIs regulate gene expression through chromatin-based mechanisms, however in most cases this has not been directly tested. Here, we...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753492/ https://www.ncbi.nlm.nih.gov/pubmed/31363749 http://dx.doi.org/10.1093/nar/gkz607 |