Recruitment of Reverse Transcriptase-Cas1 Fusion Proteins by Type VI-A CRISPR-Cas Systems

Type VI CRISPR–Cas systems contain a single effector nuclease (Cas13) that exclusively targets single-stranded RNA. It remains unknown how these systems acquire spacers. It has been suggested that type VI systems with adaptation modules can acquire spacers from RNA bacteriophages, but sequence simil...

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Detalles Bibliográficos
Autores principales: Toro, Nicolás, Mestre, Mario Rodríguez, Martínez-Abarca, Francisco, González-Delgado, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753606/
https://www.ncbi.nlm.nih.gov/pubmed/31572350
http://dx.doi.org/10.3389/fmicb.2019.02160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753606/
https://www.ncbi.nlm.nih.gov/pubmed/31572350
http://dx.doi.org/10.3389/fmicb.2019.02160

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