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Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal

Doxorubicin (Dox), an antitumor antibiotic, has therapeutic effects on many kinds of tumors. However, Dox can produce some serious side effects that limit its clinical application. Thus, exploration of effective drug targets or active lead compounds against Dox-induced organ damage is necessary. Dio...

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Detalles Bibliográficos
Autores principales: Song, Shasha, Chu, Liang, Liang, Huifang, Chen, Jin, Liang, Junnan, Huang, Zhao, Zhang, Bixiang, Chen, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753638/
https://www.ncbi.nlm.nih.gov/pubmed/31572199
http://dx.doi.org/10.3389/fphar.2019.01030