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Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids
Atorvastatin calcium (Lipitor(®), Sortis(®)) is a well-established cholesterol synthesis enzyme (CSE) inhibitor commonly used in the therapy of hypercholesterolemia. This drug is known to be sensitive to acid treatment, but only little data has been published on the structures of the degradation pro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753681/ https://www.ncbi.nlm.nih.gov/pubmed/31579096 http://dx.doi.org/10.3762/bjoc.15.206 |