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Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids

Atorvastatin calcium (Lipitor(®), Sortis(®)) is a well-established cholesterol synthesis enzyme (CSE) inhibitor commonly used in the therapy of hypercholesterolemia. This drug is known to be sensitive to acid treatment, but only little data has been published on the structures of the degradation pro...

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Detalles Bibliográficos
Autores principales:	Krauß, Jürgen, Klimt, Monika, Luber, Markus, Mayer, Peter, Bracher, Franz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2019
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753681/ https://www.ncbi.nlm.nih.gov/pubmed/31579096 http://dx.doi.org/10.3762/bjoc.15.206

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