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Δ(9)-Tetrahydrocannabinol Derivative-Loaded Nanoformulation Lowers Intraocular Pressure in Normotensive Rabbits

PURPOSE: Δ(9)-Tetrahydrocannabinol-valine-hemisuccinate, a hydrophilic prodrug of Δ(9)-tetrahydrocannabinol, synthesized with the aim of improving the ocular bioavailability of the parent molecule, was investigated in a lipid-based nanoparticle dosage form for ocular delivery. METHODS: Solid lipid n...

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Detalles Bibliográficos
Autores principales:	Taskar, Pranjal S., Patil, Akash, Lakhani, Prit, Ashour, Eman, Gul, Waseem, ElSohly, Mahmoud A., Murphy, Brian, Majumdar, Soumyajit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753841/ https://www.ncbi.nlm.nih.gov/pubmed/31588378 http://dx.doi.org/10.1167/tvst.8.5.15

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