Gentamicin Affects the Bioenergetics of Isolated Mitochondria and Collapses the Mitochondrial Membrane Potential in Cochlear Sensory Hair Cells

Aminoglycoside antibiotics are widely prescribed to treat a variety of serious bacterial infections. They are extremely useful clinical tools, but have adverse side effects such as oto- and nephrotoxicity. Once inside a cell they are thought to cause mitochondrial dysfunction, subsequently leading t...

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Detalles Bibliográficos
Autores principales: O’Reilly, Molly, Young, Luke, Kirkwood, Nerissa K., Richardson, Guy P., Kros, Corné J., Moore, Anthony L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753894/
https://www.ncbi.nlm.nih.gov/pubmed/31572129
http://dx.doi.org/10.3389/fncel.2019.00416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753894/
https://www.ncbi.nlm.nih.gov/pubmed/31572129
http://dx.doi.org/10.3389/fncel.2019.00416

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