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Integrating Genome-Wide Association Studies With Pathway Analysis and Gene Expression Analysis Highlights Novel Osteoarthritis Risk Pathways and Genes

Osteoarthritis (OA) is the most common degenerative joint disorder worldwide. To identify more genetic signals, genome-wide association study (GWAS) has been widely used and elucidated some OA susceptibility genes. However, these susceptibility genes could only explain only a small part of heritabil...

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Detalles Bibliográficos
Autores principales: Gao, Feng, Yao, Yu, Zhang, Yiwei, Tian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753977/
https://www.ncbi.nlm.nih.gov/pubmed/31572443
http://dx.doi.org/10.3389/fgene.2019.00827