Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network

Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, into the C. elegans endoderm GRN. While some natural isolates show a nearly...

Descripción completa

Detalles Bibliográficos
Autores principales: Torres Cleuren, Yamila N, Ewe, Chee Kiang, Chipman, Kyle C, Mears, Emily R, Wood, Cricket G, Al-Alami, Coco Emma Alma, Alcorn, Melissa R, Turner, Thomas L, Joshi, Pradeep M, Snell, Russell G, Rothman, Joel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754231/
https://www.ncbi.nlm.nih.gov/pubmed/31414984
http://dx.doi.org/10.7554/eLife.48220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754231/
https://www.ncbi.nlm.nih.gov/pubmed/31414984
http://dx.doi.org/10.7554/eLife.48220

Ejemplares similares