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Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network
Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, into the C. elegans endoderm GRN. While some natural isolates show a nearly...
Autores principales: | Torres Cleuren, Yamila N, Ewe, Chee Kiang, Chipman, Kyle C, Mears, Emily R, Wood, Cricket G, Al-Alami, Coco Emma Alma, Alcorn, Melissa R, Turner, Thomas L, Joshi, Pradeep M, Snell, Russell G, Rothman, Joel H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754231/ https://www.ncbi.nlm.nih.gov/pubmed/31414984 http://dx.doi.org/10.7554/eLife.48220 |
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