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Montelukast Prevents Early Diabetic Retinopathy in Mice

Chronic inflammation and oxidative stress are critical components in the pathogenic cascade of early diabetic retinopathy, characterized by neuronal and vascular degeneration. We investigated pharmacologic inhibition of the proinflammatory leukotriene cascade for therapeutic benefit in early diabeti...

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Detalles Bibliográficos
Autores principales: Bapputty, Reena, Talahalli, Ramaprasad, Zarini, Simona, Samuels, Ivy, Murphy, Robert, Gubitosi-Klug, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754245/
https://www.ncbi.nlm.nih.gov/pubmed/31350303
http://dx.doi.org/10.2337/db19-0026