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Follicular regulatory T cells control humoral and allergic immunity by restraining early B cell responses

Follicular regulatory T (Tfr) cells have specialized roles in modulating Tfh help to B cells. However, the precise role of Tfr cells in controlling antibody responses to foreign and auto-antigens in vivo is still unclear due to a lack of specific tools. We developed a Tfr-deleter mouse that selectiv...

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Detalles Bibliográficos
Autores principales: Clement, Rachel L., Daccache, Joe, Mohammed, Mostafa T., Diallo, Alos, Blazar, Bruce R., Kuchroo, Vijay K., Lovitch, Scott B., Sharpe, Arlene H., Sage, Peter T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754271/
https://www.ncbi.nlm.nih.gov/pubmed/31477921
http://dx.doi.org/10.1038/s41590-019-0472-4