L-arginine supplementation and thromboxane synthase inhibition increases cerebral blood flow in experimental cerebral malaria

Cerebral malaria pathogenesis involves vascular dysfunction with low nitric oxide (NO) bioavailability, vasoconstriction and impaired vasodilation, leading to ischemia, tissue hypoxia and ultimately death. Cerebral blood flow (CBF) involves NO and other pathways, including arachidonic acid (AA)-deri...

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Detalles Bibliográficos
Autores principales: Moreira, Aline S., Estato, Vanessa, Malvar, David C., Sanches, Guilherme S., Gomes, Fabiana, Tibirica, Eduardo, Daniel-Ribeiro, Cláudio Tadeu, Carvalho, Leonardo J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754365/
https://www.ncbi.nlm.nih.gov/pubmed/31541129
http://dx.doi.org/10.1038/s41598-019-49855-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754365/
https://www.ncbi.nlm.nih.gov/pubmed/31541129
http://dx.doi.org/10.1038/s41598-019-49855-x

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