Genome-wide recombination map construction from single individuals using linked-read sequencing

Meiotic recombination rates vary across the genome, often involving localized crossover hotspots and coldspots. Studying the molecular basis and mechanisms underlying this variation has been challenging due to the high cost and effort required to construct individualized genome-wide maps of recombin...

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Detalles Bibliográficos
Autores principales: Dréau, Andreea, Venu, Vrinda, Avdievich, Elena, Gaspar, Ludmila, Jones, Felicity C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754380/
https://www.ncbi.nlm.nih.gov/pubmed/31541091
http://dx.doi.org/10.1038/s41467-019-12210-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754380/
https://www.ncbi.nlm.nih.gov/pubmed/31541091
http://dx.doi.org/10.1038/s41467-019-12210-9

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