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Cigarette Smoke Exposure Induces Retrograde Trafficking of CFTR to the Endoplasmic Reticulum

Chronic obstructive pulmonary disease (COPD), which is most commonly caused by cigarette smoke (CS) exposure, is the third leading cause of death worldwide. The cystic fibrosis transmembrane conductance regulator (CFTR) is an apical membrane anion channel that is widely expressed in epithelia throug...

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Detalles Bibliográficos
Autores principales: Marklew, Abigail J., Patel, Waseema, Moore, Patrick J., Tan, Chong D., Smith, Amanda J., Sassano, M. Flori, Gray, Michael A., Tarran, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754399/
https://www.ncbi.nlm.nih.gov/pubmed/31541117
http://dx.doi.org/10.1038/s41598-019-49544-9