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A mass spectrometry-based assay using metabolic labeling to rapidly monitor chromatin accessibility of modified histone proteins

Histone post-translational modifications (PTMs) contribute to chromatin accessibility due to their chemical properties and their ability to recruit enzymes responsible for DNA readout and chromatin remodeling. To date, more than 400 different histone PTMs and thousands of combinations of PTMs have b...

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Detalles Bibliográficos
Autores principales: Sidoli, Simone, Lopes, Mariana, Lund, Peder J., Goldman, Naomi, Fasolino, Maria, Coradin, Mariel, Kulej, Katarzyna, Bhanu, Natarajan V., Vahedi, Golnaz, Garcia, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754405/
https://www.ncbi.nlm.nih.gov/pubmed/31541121
http://dx.doi.org/10.1038/s41598-019-49894-4