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Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development
Tet-mediated DNA demethylation plays an important role in shaping the epigenetic landscape and chromatin accessibility to control gene expression. While several studies demonstrated pivotal roles of Tet in regulating embryonic development, little is known about their functions in heart development....
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754421/ https://www.ncbi.nlm.nih.gov/pubmed/31541101 http://dx.doi.org/10.1038/s41467-019-12325-z |