Haploinsufficiency of Transferrin Receptor 1 Impairs Angiogenesis with Reduced Mitochondrial Complex I in Mice with Limb Ischemia

Limb ischemia (LI) is a major consequence of peripheral artery disease (PAD) with a high mortality rate. Iron is an essential mineral to maintain physiological function of multiple organs. Intracellular iron transport is regulated by transferrin receptor 1 (TfR1). Although increase in serum ferritin...

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Detalles Bibliográficos
Autores principales: Okuno, Keisuke, Naito, Yoshiro, Yasumura, Seiki, Sawada, Hisashi, Asakura, Masanori, Masuyama, Tohru, Ishihara, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754437/
https://www.ncbi.nlm.nih.gov/pubmed/31541184
http://dx.doi.org/10.1038/s41598-019-49983-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754437/
https://www.ncbi.nlm.nih.gov/pubmed/31541184
http://dx.doi.org/10.1038/s41598-019-49983-4

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