Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes

Cardiomyocytes from human induced pluripotent stem cells (hiPSC-CMs) are increasingly recognized as valuable for determining the effects of drugs on ion channels but they do not always accurately predict contractile responses of the human heart. This is in part attributable to their immaturity but t...

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Detalles Bibliográficos
Autores principales: van Meer, Berend J., Krotenberg, Ana, Sala, Luca, Davis, Richard P., Eschenhagen, Thomas, Denning, Chris, Tertoolen, Leon G. J., Mummery, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754438/
https://www.ncbi.nlm.nih.gov/pubmed/31541103
http://dx.doi.org/10.1038/s41467-019-12354-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754438/
https://www.ncbi.nlm.nih.gov/pubmed/31541103
http://dx.doi.org/10.1038/s41467-019-12354-8

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