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The Human Papillomavirus (HPV) E1 protein regulates the expression of cellular genes involved in immune response

The Human Papillomavirus (HPV) E1 protein is the only viral protein with enzymatic activity. The main known function of this protein is the regulation of the viral DNA replication. Nevertheless, it has been demonstrated that the ablation of HPV18 E1 mRNA in HeLa cells promotes a deregulation of seve...

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Detalles Bibliográficos
Autores principales: Castro-Muñoz, Leonardo Josué, Manzo-Merino, Joaquín, Muñoz-Bello, J. Omar, Olmedo-Nieva, Leslie, Cedro-Tanda, Alberto, Alfaro-Ruiz, Luis Alberto, Hidalgo-Miranda, Alfredo, Madrid-Marina, Vicente, Lizano, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754496/
https://www.ncbi.nlm.nih.gov/pubmed/31541186
http://dx.doi.org/10.1038/s41598-019-49886-4