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Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction
Glucagon promotes hepatic gluconeogenesis and maintains whole-body glucose levels during fasting. The regulatory factors that are involved in fasting glucagon response are not well understood. Here we report a role of p52, a key activator of the noncanonical nuclear factor-kappaB signaling, in hepat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754499/ https://www.ncbi.nlm.nih.gov/pubmed/31541100 http://dx.doi.org/10.1038/s41467-019-12351-x |