Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor

Single-molecule force spectroscopy has provided unprecedented insights into protein folding, force regulation, and function. So far, the field has relied primarily on atomic force microscope and optical tweezers assays that, while powerful, are limited in force resolution, throughput, and require fe...

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Detalles Bibliográficos
Autores principales: Löf, Achim, Walker, Philipp U., Sedlak, Steffen M., Gruber, Sophia, Obser, Tobias, Brehm, Maria A., Benoit, Martin, Lipfert, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754583/
https://www.ncbi.nlm.nih.gov/pubmed/31462494
http://dx.doi.org/10.1073/pnas.1901794116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754583/
https://www.ncbi.nlm.nih.gov/pubmed/31462494
http://dx.doi.org/10.1073/pnas.1901794116

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