Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts

Telomerase is an enzymatic ribonucleoprotein complex that acts as a reverse transcriptase in the elongation of telomeres. Telomerase activity is well documented in embryonic stem cells and the vast majority of tumor cells, but its role in somatic cells remains to be understood. Here, we report an un...

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Detalles Bibliográficos
Autores principales: Sun, Linlin, Chiang, Jeffrey Y., Choi, Ji Young, Xiong, Zheng-Mei, Mao, Xiaojing, Collins, Francis S., Hodes, Richard J., Cao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754593/
https://www.ncbi.nlm.nih.gov/pubmed/31481614
http://dx.doi.org/10.1073/pnas.1907199116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754593/
https://www.ncbi.nlm.nih.gov/pubmed/31481614
http://dx.doi.org/10.1073/pnas.1907199116

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