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Efficient marker free CRISPR/Cas9 genome editing for functional analysis of gene families in filamentous fungi

BACKGROUND: CRISPR/Cas9 mediated genome editing has expedited the way of constructing multiple gene alterations in filamentous fungi, whereas traditional methods are time-consuming and can be of mutagenic nature. These developments allow the study of large gene families that contain putatively redun...

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Detalles Bibliográficos
Autores principales: van Leeuwe, Tim M., Arentshorst, Mark, Ernst, Tim, Alazi, Ebru, Punt, Peter J., Ram, Arthur F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754632/
https://www.ncbi.nlm.nih.gov/pubmed/31559019
http://dx.doi.org/10.1186/s40694-019-0076-7