Ecdysone-Induced 3D Chromatin Reorganization Involves Active Enhancers Bound by Pipsqueak and Polycomb

Evidence suggests that Polycomb (Pc) is present at chromatin loop anchors in Drosophila. Pc is recruited to DNA through interactions with the GAGA binding factors GAF and Pipsqueak (Psq). Using HiChIP in Drosophila cells, we find that the psq gene, which has diverse roles in development and tumorige...

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Detalles Bibliográficos
Autores principales: Gutierrez-Perez, Irene, Rowley, M. Jordan, Lyu, Xiaowen, Valadez-Graham, Viviana, Vallejo, Diana M., Ballesta-Illan, Esther, Lopez-Atalaya, Jose P., Kremsky, Isaac, Caparros, Esther, Corces, Victor G., Dominguez, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754745/
https://www.ncbi.nlm.nih.gov/pubmed/31484080
http://dx.doi.org/10.1016/j.celrep.2019.07.096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754745/
https://www.ncbi.nlm.nih.gov/pubmed/31484080
http://dx.doi.org/10.1016/j.celrep.2019.07.096

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