Cargando…

The Sirt1/P53 Axis in Diabetic Intervertebral Disc Degeneration Pathogenesis and Therapeutics

Intervertebral disc degeneration (IDD) is one of the major causes of low back pain. Diabetes is a risk factor for IDD and may aggravate IDD in rats; however, the mechanism is poorly understood. Previously, we demonstrated that apoptosis and senescence were increased in diabetic nucleus pulposus (NP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zengjie, Lin, Jialiang, Nisar, Majid, Chen, Tingting, Xu, Tianzhen, Zheng, Gang, Wang, Chenggui, Jin, Haiming, Chen, Jiaoxiang, Gao, Weiyang, Tian, Naifeng, Wang, Xiangyang, Zhang, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754956/
https://www.ncbi.nlm.nih.gov/pubmed/31583043
http://dx.doi.org/10.1155/2019/7959573